{"id":15091,"date":"2023-04-17T19:06:48","date_gmt":"2023-04-17T19:06:48","guid":{"rendered":"https:\/\/www.goodacademic.com\/blog\/questions\/genome-wide-crispr-cas9-screening-reveals-ubiquitous-t-cell-cancer-targeting-via-the-monomorphic-mhc-class-i-related-protein-mr1\/"},"modified":"2023-04-17T19:06:48","modified_gmt":"2023-04-17T19:06:48","slug":"genome-wide-crispr-cas9-screening-reveals-ubiquitous-t-cell-cancer-targeting-via-the-monomorphic-mhc-class-i-related-protein-mr1","status":"publish","type":"questions","link":"https:\/\/www.goodacademic.com\/blog\/questions\/genome-wide-crispr-cas9-screening-reveals-ubiquitous-t-cell-cancer-targeting-via-the-monomorphic-mhc-class-i-related-protein-mr1\/","title":{"rendered":"Genome-wide CRISPR-Cas9 Screening Reveals Ubiquitous T cell Cancer Targeting via the monomorphic MHC class I related protein MR1"},"content":{"rendered":"<p>Crowther, M.D., G. Dolton, M. Legut, M.E. Caillaud, A. Lloyd, M. Attaf, S. A. E. Galloway, C. Rius, C.P. Farrell, B. Szomolay, A. Ager, A.L. Parker, A. Fuller, M. Donia, J. McCluskey, J. Rossjohn, I. M. Svane, J. D. Phillips &amp; A. K. Sewell . Genome-wide CRISPR\u2013Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1. Nature Immunology 21,178\u2013185 (2020)<\/p>\n<div><\/div>\n<div>Using this article, create a presentation (no more than 20 slides) to discuss this article.&nbsp;<\/div>\n<div>Major points to include:<\/div>\n<div>1. Brief introduction of the topic and background information<\/div>\n<div>2. Identification of the pathways involved<\/div>\n<div>3. Identification of the hypothesis of the research paper<\/div>\n<div>4. Major findings description (with figures from the text)<\/div>\n<div>5. Pitfalls and limitations<\/div>\n<div>6. Identification of the next experiment&nbsp;<\/div>\n<div>7. Conclusion<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Crowther, M.D., G. Dolton, M. Legut, M.E. Caillaud, A. Lloyd, M. Attaf, S. A. E. Galloway, C. Rius, C.P. Farrell, B. Szomolay, A. Ager, A.L. Parker, A. Fuller, M. Donia, J. McCluskey, J. Rossjohn, I. M. Svane, J. D. Phillips &amp; A. K. Sewell . Genome-wide CRISPR\u2013Cas9 screening reveals ubiquitous T cell cancer targeting via [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":[],"disciplines":[275],"paper_types":[],"tagged":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.goodacademic.com\/blog\/wp-json\/wp\/v2\/questions\/15091"}],"collection":[{"href":"https:\/\/www.goodacademic.com\/blog\/wp-json\/wp\/v2\/questions"}],"about":[{"href":"https:\/\/www.goodacademic.com\/blog\/wp-json\/wp\/v2\/types\/questions"}],"author":[{"embeddable":true,"href":"https:\/\/www.goodacademic.com\/blog\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.goodacademic.com\/blog\/wp-json\/wp\/v2\/comments?post=15091"}],"version-history":[{"count":0,"href":"https:\/\/www.goodacademic.com\/blog\/wp-json\/wp\/v2\/questions\/15091\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.goodacademic.com\/blog\/wp-json\/wp\/v2\/media?parent=15091"}],"wp:term":[{"taxonomy":"disciplines","embeddable":true,"href":"https:\/\/www.goodacademic.com\/blog\/wp-json\/wp\/v2\/disciplines?post=15091"},{"taxonomy":"paper_types","embeddable":true,"href":"https:\/\/www.goodacademic.com\/blog\/wp-json\/wp\/v2\/paper_types?post=15091"},{"taxonomy":"tagged","embeddable":true,"href":"https:\/\/www.goodacademic.com\/blog\/wp-json\/wp\/v2\/tagged?post=15091"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}